Genesis 22 1 And it came to pass after these things, that God tested Abraham, and said to him, Abraham; and he said, Behold, here I am. 2 And he said, Take now your son, your only son Isaac, whom you love, and go to the land of Moriah; and offer him there for a burnt offering upon one of the mountains which I will tell you. 3 And Abraham rose up early in the morning, and saddled his ass, and took two of his young men with him, and Isaac his son, and broke the wood for the burnt offering, and rose up, and went to the place of which God had told him. [Abraham left and did not tell Sarah]
After Satan taunted Sarah about what allegedly happened to her son, she hysterically inquired of everyone the whereabouts of her husband and son, going so far as to Hebron.
McBee interpretation: Four giants lived in Hebron and when she asked them to see what they could see, they reported seeing an old man about to slaughter a young man. When she heard that she cried out and died.
Leviticus Rabba: Genesis 23: 1-3
There is proof that this is so, for Isaac returned to his mother and she said to him: ' Where have you been, my son?' Said he to her: ' My father took me and led me up mountains and down hills, ' etc. ' Alas, ' she said, 'for the son of a hapless woman! Had it not been for the angel you would by now have been slain! ' ' Yes,' he said to her. Thereupon she uttered six cries, corresponding to the six blasts of the Shofar. It has been said: She had scarcely finished speaking when she died. Hence it is written, And Abraham came to mourn for Sarah, and to weep for her (ib. 23:2).
Rashi: Genesis 23: 1
And Abraham came to mourn for Sarah and to weep for her: The telling of Sarah's death directly follows the binding of Isaac, because when Sarah is told about the binding of Isaac where her son has been prepared for slaughter and then was nearly not slaughtered, her soul flew from her and she died.